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Melanin Offers Protection Against Induction of Cyclobutane Pyrimidine Dimers and 6-4 Photoproducts by UVB in Cultured Human Melanocytes¶

1 Jan 2001

Abstract excerpt

The goal of this investigation was to correlate the melanin content in human pigmentary cells with the generation of UVB-induced photoproducts and to examine the relationship between the melanin content and the removal of the photoproducts. Cultured melanocytes from light-skinned individuals synthesized less melanin and produced more cyclobutane pyrimidine dimers and 6-4 photoproducts upon UVB exposure than did...

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Identifiers

PMID: 11594056
DOI: 10.1562/0031-8655(2001)0740424mopaio2.0.co2

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