Article
Recall response to cytomegalovirus in allograft recipients: mobilization of CD57+, CD28+ cells before expansion of CD57+, CD28- cells within the CD8+ T lymphocyte compartment.
Transplantation - 15 Mar 1997
Hazzan M, Labalette M, Noel C, Lelievre G, Dessaint J P
Abstract excerpt
BACKGROUND: Strong correlations have been described between persistently elevated proportions of CD57+ (CD28-) CD8+high T lymphocytes and cytomegalovirus (CMV) infection, in healthy individuals as well as in transplant patients. We investigated whether secondary exposure to CMV triggers recall responses within the CD8 T cell compartment. METHODS: In a longitudinal study in 123 kidney recipients, we compared 17...
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