Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cerebrospinal fluid apolipoprotein E level is increased in late-onset Alzheimer's disease.

Journal of the neurological sciences - 1 Jan 1997

Merched A, Blain H, Visvikis S, Herbeth B, Jeandel C, Siest G

Abstract excerpt

Worldwide evidence has recently shown that the allele epsilon4 of apolipoprotein E (ApoE) is a genetic risk factor for Alzheimer's disease (AD) underlining the possible role of apoE in the physiopathology of AD. To evaluate the usefulness of apoE concentration in pathogenesis of AD, we measured the cerebrospinal fluid (CSF) levels of apoE. CSF apoE level was significantly higher in 38 patients with late-onset AD...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alzheimer Disease

Share to Apolipoproteins E

Share to Gene Frequency

Share to Genotype

Share to Phenotype

Source

Identifiers

PMID: 9073026
DOI: 10.1016/s0022-510x(96)00234-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cerebrospinal fluid apolipoprotein E level is increased in late-onset Alzheimer's disease.PMID 9073026Read ↗

Measurement of apolipoprotein E (apoE) in cerebrospinal fluid.Semantic proximity Read ↗

Apolipoprotein E in Cerebrospinal Fluid from Patients with Alzheimer's Disease and Other Forms of Dementia Is Reduced but without Any Correlation to the apoE4 IsoformSemantic proximity Read ↗

Apolipoprotein E levels in the cerebrospinal fluid of north Indian patients with Alzheimer's disease.Semantic proximity Read ↗

Age-dependent decline in the apolipoprotein E level in cerebrospinal fluid from control subjects and its increase in cerebrospinal fluid from patients with Alzheimer's disease.Semantic proximity Read ↗

APOE is a major susceptibility gene for Alzheimer's disease.Semantic proximity Read ↗

Relevance of the quantification of apolipoprotein E in the cerebrospinal fluid in Alzheimer's disease.Semantic proximity Read ↗

Detrimental Effects of ApoE ε4 on Blood–Brain Barrier Integrity and Their Potential Implications on the Pathogenesis of Alzheimer’s DiseaseSemantic proximity Read ↗

Protective Role of Cerebrospinal Fluid Inflammatory Cytokines in Patients with Amnestic Mild Cognitive Impairment and Early Alzheimer's Disease Carrying Apolipoprotein E4 Genotype.Semantic proximity Read ↗

The role of apolipoprotein E in the nervous systemSemantic proximity Read ↗

A quantitative and immunohistochemical study on apolipoprotein E in brain tissue in Alzheimer's disease.Semantic proximity Read ↗

Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels.Semantic proximity Read ↗

APOE epsilon4 allele is associated with reduced cerebrospinal fluid levels of Abeta42.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.