Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Use of monoclonal antibodies to detect disease associated HLA-DRB1 alleles and the shared epitope in rheumatoid arthritis.

Annals of the rheumatic diseases - 1 Feb 1997

Wicks I, McColl G, D'Amico A, Dougherty L, Tait B

Abstract excerpt

OBJECTIVE: To use a panel of monoclonal antibodies (Mab) which recognise HLA class II alleles associated with rheumatoid arthritis for fluorescence activated cell sorter (FACS) analysis of peripheral blood mononuclear cells (PBMNC) from patients with early and established rheumatoid arthritis and to compare these results against DNA oligotyping of HLA class II molecules in the same patients. METHODS: 27 patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Prognosis
Share to Alleles
Share to Antibodies, Monoclonal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epitopes

Share to Flow Cytometry

Share to Histocompatibility Testing

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Source

Open in PubMed Open full text

Identifiers

PMID: 9068289
DOI: 10.1136/ard.56.2.135
PMCID: PMC1752326

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Use of monoclonal antibodies to detect disease associated HLA-DRB1 alleles and the shared epitope in rheumatoid arthritis.PMID 9068289Read ↗

A Molecular Analysis of the Shared Epitope Hypothesis: Binding of Arthritogenic Peptides to DRB1*04 Alleles.Semantic proximity Read ↗

Barcode‐Enabled Sequencing of Plasmablast Antibody Repertoires in Rheumatoid ArthritisSemantic proximity Read ↗

A routine assay for the direct analysis of HLA-DR-related shared epitope and B27 alleles in chronic inflammatory arthritis.Semantic proximity Read ↗

HLA-DRB1 typing in rheumatoid arthritis: predicting response to specific treatments.Semantic proximity Read ↗

The influence of HLA-DRB1 genes on disease severity in rheumatoid arthritis.Semantic proximity Read ↗

HLA-DP epitope typing using monoclonal antibodies.Semantic proximity Read ↗

Antibodies against HLA-DP recognize broadly expressed epitopes.Semantic proximity Read ↗

Cloning and expression of a novel human antibody–antigen pair associated with Felty's syndromeSemantic proximity Read ↗

A rapid and efficient strategy to generate allele-specific anti-HLA monoclonal antibodies.Semantic proximity Read ↗

Specificity of HLA monoclonal antibodies and their use to determine HLA expression on lymphocytes and peripheral blood stem cells.Semantic proximity Read ↗

Disease-associated human histocompatibility leukocyte antigen determinants in patients with seropositive rheumatoid arthritis. Functional role in antigen-specific and allogeneic T cell recognition.Semantic proximity Read ↗

Functional Analysis of the Anti-adalimumab Response Using Patient-derived Monoclonal AntibodiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.