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Article

Barcode‐Enabled Sequencing of Plasmablast Antibody Repertoires in Rheumatoid Arthritis

25 Jun 2014

Abstract excerpt

OBJECTIVE: A hallmark of rheumatoid arthritis (RA) is the production of autoantibodies, including anti-citrullinated protein antibodies (ACPAs). Nevertheless, the specific targets of these autoantibodies remain incompletely defined. During an immune response, B cells specific for the inciting antigen(s) are activated and differentiate into plasmablasts, which are released into the blood. We undertook this study...

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PMID: 24965753
DOI: 10.1002/art.38754

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