Article
Surface expression of a glycolytic enzyme, α‐enolase, recognized by autoantibodies in connective tissue disorders
30 Nov 2000
Abstract excerpt
In systemic autoimmune diseases, autoantibodies specific for alpha-enolase are detected more frequently in patients with active renal involvement. To analyze the properties of anti-alpha-enolase antibodies and the distribution of the enzyme in the cell, mouse monoclonal and polyclonal antibodies were obtained from mice immunized with a glutathione-S-transferase-alpha-enolase fusion protein. Anti-alpha-enolase...
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