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[Topographic genomapping of p53 mutations in non-small cell lung cancer using in situ PCR].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Feb 1997

Ebina M, Linnoila R I, Nukiwa T

Abstract excerpt

We examined topographic distribution of p53 mutations using in situ PCR in three primary non-small cell lung cancers, showing distinct patterns of variable p53 overexpression by immunohistochemistry (Ebina, et al:Cancer Res. 54:2496, 1994). All tumor cell nuclei, regardless of the status of p53 overexpression, demonstrated homogeneous distribution of mutant p53 with specific primers, suggesting only subgroups of...

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PMID: 9063476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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