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Article

Alphaherpesviruses and the Cytoskeleton in Neuronal Infections

27 Jun 2011

Abstract excerpt

Following infection of exposed peripheral tissues, neurotropic alphaherpesviruses invade nerve endings and deposit their DNA genomes into the nuclei of neurons resident in ganglia of the peripheral nervous system. The end result of these events is the establishment of a life-long latent infection. Neuroinvasion typically requires efficient viral transmission through a polarized epithelium followed by...

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PMID: 21994765
DOI: 10.3390/v3070941

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