Article
Familial defective apolipoprotein B-100 in hypercholesterolemic Chinese Canadians: identification of a unique haplotype of the apolipoprotein B-100 allele.
Atherosclerosis - 1 Dec 1997
Abdel-Wareth L O, Pimstone S N, Lagarde J P, Raisonnier A, Benlian P, Pritchard H, Hayden M R, Frohlich J J
Abstract excerpt
Familial defective apo B-100 (FDB) is an autosomal dominant condition resulting in hypercholesterolemia. It is generally observed in 1-6% of hypercholesterolemic subjects in Caucasian populations studied. There are, thus far, no reports characterizing the frequency and phenotype of FDB in a Chine...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Apolipoprotein B-100
- Apolipoproteins B
- Canada
- China
- Female
- Gene Frequency
- Haplotypes
- Humans
- Hypercholesterolemia
- Male
- Middle Aged
- Pedigree
- Phenotype
- Prevalence