Article
Single amino acid substitutions in the glycoprotein B carboxy terminus influence the fusion from without property of herpes simplex virus type 1.
The Journal of general virology - 1 Jul 1995
Lingen M, Seck T, Weise K, Falke D
Abstract excerpt
Syncytial mutations of herpes simplex virus type 1 (HSV-1) strains ANG, ANG path, HFEM, tsB5 and HSZP cause extensive cell fusion and were mapped to the cytoplasmic domain of glycoprotein B (gB), within the syn 3 locus. These strains are so far the only ones which show the phenotype 'fusion from...
Topics
- Alanine
- Amino Acid Sequence
- Amino Acids
- Animals
- Cell Fusion
- Chlorocebus aethiops
- Cricetinae
- Cytopathogenic Effect, Viral
- Enzyme-Linked Immunosorbent Assay
- Herpesvirus 1, Human
- Kidney
- Phenotype
- Recombination, Genetic
- Restriction Mapping
- Valine
- Vero Cells
- Viral Envelope Proteins