Cyclosporin A resistance of herpes simplex virus-induced "fusion from within" as a phenotypical marker of mutations in the Syn 3 locus of the glycoprotein B gene.

doi:10.1007/BF01703606

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Article

Cyclosporin A resistance of herpes simplex virus-induced "fusion from within" as a phenotypical marker of mutations in the Syn 3 locus of the glycoprotein B gene.

Virus genes - 1 Jan 1994

Walev I, Lingen M, Lazzaro M, Weise K, Falke D

Abstract excerpt

We here report research in which nine strains of Herpes simplex virus (HSV) with fusing activity were investigated in order to establish precise phenotypical markers of mutations in the carboxy terminus of glycoprotein B (gB). The gene region encoding the carboxy terminus of gB was isolated, then...

Topics

Animals
Cell Fusion
Cell Line
Cyclosporine
Drug Resistance, Microbial
Genes, Viral
Genetic Markers
Humans
Mutation
Phenotype
Simplexvirus
Viral Envelope Proteins
Viral Fusion Proteins

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