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Hepatitis C Virus Core and E2 Protein Expression in Transgenic Mice

1 Mar 1997

Abstract excerpt

Transgenic mice have been produced that express the hepatitis C virus (HCV) core protein in the liver under the transcriptional control of the mouse major urinary protein promoter. These animals express the full length core protein in cytoplasm of their hepatocytes at levels comparable to those detected in naturally infected patients, without histological or biochemical evidence of liver disease or hepatocellular...

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PMID: 9049225
DOI: 10.1002/hep.510250338

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