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Article

A Candida biofilm-induced pathway for matrix glucan delivery: implications for drug resistance.

PLoS pathogens - 1 Jan 2012

Taff Heather T, Nett Jeniel E, Zarnowski Robert, Ross Kelly M, Sanchez Hiram, Cain Mike T, Hamaker Jessica, Mitchell Aaron P, Andes David R

Abstract excerpt

Extracellular polysaccharides are key constituents of the biofilm matrix of many microorganisms. One critical carbohydrate component of Candida albicans biofilms, β-1,3 glucan, has been linked to biofilm protection from antifungal agents. In this study, we identify three glucan modification enzymes that function to deliver glucan from the cell to the extracellular matrix. These enzymes include two predicted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22876186
DOI: 10.1371/journal.ppat.1002848
PMCID: PMC3410897

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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