Article
Absence of the A1252G mutation in alpha 1-antichymotrypsin in a North American population suffering from dementia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Feb 1997
Gilfix B M, Briones L
Abstract excerpt
Associations have been reported between polymorphisms in the gene for alpha 1-antichymotrypsin (ACT) and both Alzheimer's disease (AD) and cerebrovascular disease. An A-to-G substitution at nucleotide position 1,252 of ACT that produces a methionine to valine substitution at codon 389 has been fo...
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