Article
Increased frequency of the alpha-1-antichymotrypsin T allele in cerebral amyloid angiopathy.
Neuropathology : official journal of the Japanese Society of Neuropathology - 1 Sept 2000
Durany N, Ravid R, Riederer P, Cruz-Sánchez F F
Abstract excerpt
Cerebral amyloid angiopathy (CAA) is a process of unknown etiology characterized by amyloid deposition in the wall of small cerebral and meningeal blood vessels. CAA is also a feature of Alzheimer's disease (AD) and of a subgroup of elderly people. Alpha-1-Antichymotrypsin (ACT) is a serum glycoprotein frequently associated with vascular and senile plaque amyloid. The ACT gene is known to have a bi-allele...
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