Article
Associations between candidate loci angiotensin-converting enzyme and angiotensinogen with coronary heart disease and myocardial infarction: the NHLBI Family Heart Study.
Annals of epidemiology - 1 Jan 1997
Ludwig E H, Borecki I B, Ellison R C, Folsom A R, Heiss G, Higgins M, Lalouel J M, Province M A, Rao D C
Abstract excerpt
Angiotensin-converting enzyme (ACE) and angiotensinogen (AGT) are major components of the renin-angiotensin systems. An association between myocardial infarction (MI) and the ACE DD genotype of the insertion/deletion (ID) polymorphism in intron 16 of the ACE gene has been reported. However, other similarly designed studies have not found such an association. Angiotensin II, the product of AGT, has a direct effect...
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