Article
Structure-function relationships of 3 beta-hydroxysteroid dehydrogenase: contribution made by the molecular genetics of 3 beta-hydroxysteroid dehydrogenase deficiency.
Steroids - 1 Jan 1997
Morel Y, Mébarki F, Rhéaume E, Sanchez R, Forest M G, Simard J
Abstract excerpt
The transformation of delta 5-3 beta-hydroxysteroids into the corresponding delta 4-3-keto-steroids is an essential step for the biosynthesis of all classes of active steroids: progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. These steroid hormones play a crucial role...
Topics
- 3-Hydroxysteroid Dehydrogenases
- Adolescent
- Amino Acid Sequence
- Animals
- Binding Sites
- Cattle
- Cell Membrane
- Child
- Child, Preschool
- Cricetinae
- Disorders of Sex Development
- Female
- Humans
- Infant, Newborn
- Isoenzymes
- Male
- Metabolic Diseases
- Mice