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Article

Population size and radiosensitivity of murine hematopoietic endogenous long-term repopulating cells.

Blood - 1 Feb 1997

McCarthy K F

Abstract excerpt

A new assay is described that measures the numbers (n) of endogenous long-term repopulating cells (eLTRC) surviving sublethal irradiation. The assay is based on analysis of variances of Pgk-1 phenotypes within groups of sublethally irradiated Pgk-1(a/b) mice. When ln n is plotted as a function of dose, the radiosensitivity (D0) is the negative reciprocal of the slope and the gamma-intercept is N or total numbers...

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PMID: 9028314

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