Article
Cloning and sequencing of the mouse Gli2 gene: localization to the Dominant hemimelia critical region.
Genomics - 15 Jan 1997
Hughes D C, Allen J, Morley G, Sutherland K, Ahmed W, Prosser J, Lettice L, Allan G, Mattei M G, Farrall M, Hill R E
Abstract excerpt
The GLI family of zinc finger genes has been implicated in both neoplastic and developmental disorders. We have cloned and sequenced the mouse homolog of the zinc finger gene Gli2 and demonstrated significant similarity to the human GLI3 gene. We have also localized Gli2 to mouse chromosome 1, in...
Topics
- Amino Acid Sequence
- Animals
- Chromosome Mapping
- Cloning, Molecular
- DNA, Complementary
- DNA-Binding Proteins
- Ectromelia
- Genes, Dominant
- Humans
- Kruppel-Like Transcription Factors
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Inbred Strains
- Molecular Sequence Data
- Mutation
- Nerve Tissue Proteins
- Nuclear Proteins