Article
DNA sequences downstream from the vitamin D response element of the rat osteocalcin gene are required for ligand-dependent transactivation.
Molecular endocrinology (Baltimore, Md.) - 1 Feb 1997
Sneddon W B, Bogado C E, Kiernan M S, Demay M B
Abstract excerpt
The sequences in the rat osteocalcin gene that lie 3' to the vitamin D response element (VDRE) have been shown to augment transcriptional activation by 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3]. These DNA sequences, however, are unable to bind the VDR or mediate 1,25-(OH)2D3 responsiveness independ...
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