Article
Transcriptional repression of the rat osteocalcin gene: role of two intronic CCTCCT motifs.
Endocrinology - 1 Sept 1999
Kearns A E, Goto K, Gianakakos G, Lippmann W, Demay M B
Abstract excerpt
The regulation of osteocalcin gene transcription is complex, involving multiple positive and negative regulators. Previous studies have demonstrated that an intronic sequence, TTTCTTT (+118 to +124) is capable of mediating transcriptional repression of osteocalcin-CAT fusion genes in cells of the...
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