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Article

α-spectrin is required for germline cell division and differentiation in the Drosophila ovary

1 Dec 1996

Abstract excerpt

During Drosophila oogenesis, developing germline cysts are spanned by a large cytoplasmic structure called a fusome, containing alpha-spectrin and the adducin-like product of the hu-li tai shao (hts) gene. We found that fusomes contain two additional membrane skeletal proteins: beta-spectrin and ankyrin. hts was shown previously to be required for cyst formation and oocyte differentiation; the role of the fusome...

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PMID: 9012516
DOI: 10.1242/dev.122.12.3959

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α-spectrin is required for germline cell division and differentiation in the Drosophila ovaryPMID 9012516Read ↗

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α-Spectrin and integrins act together to regulate actomyosin and columnarization, and to maintain a monolayered follicular epithelium.Semantic proximity Read ↗

A spectraplakin is enriched on the fusome and organizes microtubules during oocyte specification in Drosophila.Semantic proximity Read ↗

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