Article
Connexin 37 mutations in rat hepatic angiosarcomas induced by vinyl chloride.
Cancer research - 1 Feb 1997
Saito T, Barbin A, Omori Y, Yamasaki H
Abstract excerpt
Connexin genes have been shown to restore normal cell growth when transfected into certain tumorigenic cells and thus are considered to form a family of tumor suppressor genes. In this study, we have analyzed mutations of the connexin 37 (Cx37) gene in rat hepatic angiosarcomas induced by vinyl chloride. A total of 25 rat liver tumors (22 hepatic angiosarcomas and 3 hepatocellular carcinomas) were analyzed by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
