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Article

Estimating the age of alleles by use of intraallelic variability.

American journal of human genetics - 1 Feb 1997

Slatkin M, Rannala B

Abstract excerpt

A method is presented for estimating the age of an allele by use of its frequency and the extent of variation among different copies. The method uses the joint distribution of the number of copies in a population sample and the coalescence times of the intraallelic gene genealogy conditioned on the number of copies. The linear birth-death process is used to approximate the dynamics of a rare allele in a finite...

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Source

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Identifiers

PMID: 9012419
PMCID: PMC1712388

Genes

CFTR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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