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Article

Estimating the age of mutant disease alleles based on linkage disequilibrium.

Human heredity - 1 Jan 2000

Guo S W, Xiong M

Abstract excerpt

With more and more disease genes being mapped and/or cloned, there is a growing interest in dating the age of underlying mutations. The knowledge of the age of mutation is important to finely map disease genes by linkage disequilibrium mapping. It would also help us understand the origin, evolution, and dispersion of the mutant disease genes. Despite increasing interests in dating disease mutations, the...

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Identifiers

PMID: 9391824
DOI: 10.1159/000154431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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