Selection of Opa+ Neisseria gonorrhoeae by limited availability of normal human serum.

doi:10.1128/iai.65.2.645-650.1997

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Article

Selection of Opa+ Neisseria gonorrhoeae by limited availability of normal human serum.

Infection and immunity - 1 Feb 1997

Bos M P, Hogan D, Belland R J

Abstract excerpt

Experimental infections of human male volunteers with Neisseria gonorrhoeae have provided valuable insights into the early stages of gonorrheal disease. Bacterial variants expressing outer membrane opacity (Opa) proteins appear to be selected from the inoculum during a period in which total recoverable numbers of bacteria decrease rapidly. This apparent survival advantage occurs simultaneously with the onset of...

Topics

Antigens, Bacterial
Bacterial Outer Membrane Proteins
Blood Bactericidal Activity
Humans
Lipopolysaccharides
Male
Neisseria gonorrhoeae
Phenotype
Sensitivity and Specificity
Sialic Acids

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PMID: 9009326
DOI: 10.1128/iai.65.2.645-650.1997
PMCID: PMC176109

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