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Article

Multiple gonococcal opacity proteins are expressed during experimental urethral infection in the male.

The Journal of experimental medicine - 1 Mar 1994

Jerse A E, Cohen M S, Drown P M, Whicker L G, Isbey S F, Seifert H S, Cannon J G

Abstract excerpt

The opacity (Opa) proteins of Neisseria gonorrhoeae are a family of outer membrane proteins demonstrating phase and antigenic variation. N. gonorrhoeae strain FA0190 has 11 opa loci that encode at least 8 antigenically distinct Opa proteins. To determine if expression of one Opa protein or a subset of them is favored during gonococcal infection, we inoculated Opa-negative variants of strain FA1090 intraurethrally...

Topics

Antigens, Bacterial
Bacterial Outer Membrane Proteins
Blotting, Western
Fimbriae Proteins
Genes, Bacterial
Humans
Lipopolysaccharides
Male
Neisseria gonorrhoeae
Phenotype
Syphilis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Urethral Diseases

Urinary Tract Infections

Source

Open in PubMed Open full text

Identifiers

PMID: 8113683
DOI: 10.1084/jem.179.3.911
PMCID: PMC2191399

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8113683-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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