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Article

Mutations affecting development of the zebrafish ear.

Development (Cambridge, England) - 1 Dec 1996

Malicki J, Schier A F, Solnica-Krezel L, Stemple D L, Neuhauss S C, Stainier D Y, Abdelilah S, Rangini Z, Zwartkruis F, Driever W

Abstract excerpt

In a large scale screen for genetic defects in zebrafish embryogenesis we identified mutations affecting several aspects of ear development, including: specification of the otic placode, growth of the otic vesicle (otocyst), otolith formation, morphogenesis of the semicircular canals and differentiation of the otic capsule. Here we report initial phenotypic and genetic characterization of 20 of these mutations...

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Identifiers

PMID: 9007247
DOI: 10.1242/dev.123.1.275

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