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Article

Complementation of defective picornavirus internal ribosome entry site (IRES) elements by the coexpression of fragments of the IRES.

Virology - 6 Jan 1997

Roberts L O, Belsham G J

Abstract excerpt

Mutant forms of the encephalomyocarditis virus (EMCV) internal ribosome entry site (IRES) have been produced and shown to be severely defective in directing internal initiation of protein synthesis within cells using the vaccinia/T7 RNA polymerase system. Mutants in different regions of the IRES were complemented in trans by coexpression of the intact EMCV IRES but not by coexpression of the related IRES elements...

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Identifiers

PMID: 9007058
DOI: 10.1006/viro.1996.8312

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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