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Article

Gene polymorphisms of tissue plasminogen activator and plasminogen activator inhibitor-1 in patients with antiphospholipid antibodies.

The Journal of rheumatology - 1 Jun 2002

Yasuda Shinsuke, Tsutsumi Akito, Atsumi Tatsuya, Bertolaccini Maria L, Ichikawa Kenji, Khamashta Munther A, Hughes Graham R V, Koike Takao

Abstract excerpt

OBJECTIVE: Impaired fibrinolytical outcomes may be one of the pathogenic factors for thrombotic events in patients with antiphospholipid antibodies (aPL). We investigated the consequences of the gene polymorphisms of tissue plasminogen activator (tPA) and plasminogen activator inhibitor-1 (PAI-1) in patients positive for aPL. METHODS: Seventy-seven Japanese and 82 British patients with aPL were examined for...

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PMID: 12064834

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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