Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Severe growth defect in a Schizosaccharomyces pombe mutant defective in intron lariat degradation.

Molecular and cellular biology - 1 Feb 1997

Nam K, Lee G, Trambley J, Devine S E, Boeke J D

Abstract excerpt

The cDNAs and genes encoding the intron lariat-debranching enzyme were isolated from the nematode Caenorhabditis elegans and the fission yeast Schizosaccharomyces pombe based on their homology with the Saccharomyces cerevisiae gene. The cDNAs were shown to be functional in an interspecific complementation experiment; they can complement an S. cerevisiae dbr1 null mutant. About 2.5% of budding yeast S. cerevisiae...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Fungal

Share to Molecular Sequence Data

Share to Mutation

Share to Restriction Mapping

Share to Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 9001235
DOI: 10.1128/MCB.17.2.809
PMCID: PMC231807

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Severe growth defect in a Schizosaccharomyces pombe mutant defective in intron lariat degradation.PMID 9001235Read ↗

Human RNA lariat debranching enzyme cDNA complements the phenotypes of Saccharomyces cerevisiae dbr1 and Schizosaccharomyces pombe dbr1 mutants.Semantic proximity Read ↗

Intronic snoRNA biosynthesis in Saccharomyces cerevisiae depends on the lariat-debranching enzyme: intron length effects and activity of a precursor snoRNA.Semantic proximity Read ↗

Cloning, expression, and complementation test of the RNA lariat debranching enzyme cDNA from mouse.Semantic proximity Read ↗

Mechanisms of intron loss and gain in the fission yeast Schizosaccharomyces.Semantic proximity Read ↗

Genome-wide identification of spliced introns using a tiling microarray.Semantic proximity Read ↗

Interconnections Between RNA-Processing Pathways Revealed by a Sequencing-Based Genetic Screen for Pre-mRNA Splicing Mutants in Fission Yeast.Semantic proximity Read ↗

Isolation and characterization of the gene encoding yeast debranching enzyme.Semantic proximity Read ↗

An Arabidopsis RNA lariat debranching enzyme is essential for embryogenesis.Semantic proximity Read ↗

Deletion of many yeast introns reveals a minority of genes that require splicing for function.Semantic proximity Read ↗

Relationship between RNA lariat debranching and Ty1 element retrotransposition.Semantic proximity Read ↗

An unknown essential function of tRNA splicing endonuclease is linked to the integrated stress response and intron debranching.Semantic proximity Read ↗

A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: purification, biochemical characterization, and identification of a leucine-rich repeat motif.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.