Role of early and late replication events in induction of apoptosis by baculoviruses.

Abstract excerpt

Autographa californica nuclear polyhedrosis virus (AcMNPV) mutants that lack the apoptotic suppressor gene p35 cause apoptosis in Spodoptera frugiperda SF21 cells. To identify a viral signal(s) that induces programmed cell death, we first defined the timing of apoptotic events during infection. A...

Topics

• Animals
• Apoptosis
• Cell Line
• Gene Expression Regulation, Viral
• Genes, Viral
• Mutation
• Nucleopolyhedroviruses
• Spodoptera
• Virus Replication