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PHYSIOLOGICAL SIGNIFICANCE OF APOPTOSIS DURING ANIMAL VIRUS INFECTION

1 Jan 2003

Abstract excerpt

Apoptosis has been considered to be a host defense mechanism against viral infection in multicellular organisms. This is based on the findings that apoptogenic mutants of insect viruses cannot grow because infected host cells die by apoptosis. This suggests that the apoptotic response of host cells has a deleterious effect on virus infection. Thus, apoptosis is an important host defense mechanism that is capable...

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PMID: 12959749
DOI: 10.1080/08830180305210

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