Article
Baculoviruses and apoptosis: the good, the bad, and the ugly.
Cell death and differentiation - 1 Feb 2001
Clem R J
Abstract excerpt
Since 1991, when a baculovirus was first shown to inhibit apoptosis of its host insect cells, considerable contributions to our knowledge of apoptosis have arisen from the study of these viruses and the anti-apoptotic genes they encode. Baculovirus anti-apoptotic genes include p35, which encodes the most broadly acting caspase inhibitor protein known, and iap (inhibitor of apoptosis) genes, which were the first...
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