Baculoviruses and apoptosis: the good, the bad, and the ugly.

doi:10.1038/sj.cdd.4400821

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Article

Baculoviruses and apoptosis: the good, the bad, and the ugly.

Cell death and differentiation - 1 Feb 2001

Clem R J

Abstract excerpt

Since 1991, when a baculovirus was first shown to inhibit apoptosis of its host insect cells, considerable contributions to our knowledge of apoptosis have arisen from the study of these viruses and the anti-apoptotic genes they encode. Baculovirus anti-apoptotic genes include p35, which encodes the most broadly acting caspase inhibitor protein known, and iap (inhibitor of apoptosis) genes, which were the first...

Topics

Animals
Apoptosis
Baculoviridae
Caspases
Cytokines
Host-Parasite Interactions
Inhibitor of Apoptosis Proteins
Insecta
Mutation
Viral Proteins
Virus Diseases
Virus Replication

Source

Open in PubMed

Identifiers

PMID: 11313715
DOI: 10.1038/sj.cdd.4400821

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