Article
Point mutations within the betaG-betaH loop of foot-and-mouth disease virus O1K affect virus attachment to target cells.
Journal of virology - 1 Feb 1997
Leippert M, Beck E, Weiland F, Pfaff E
Abstract excerpt
The amino acid sequence Arg-Gly-Asp (RGD) is a highly conserved region located on the P1D protein of most sero- and subtypes of foot-and-mouth disease virus (FMDV)and participates in binding of FMDV to their target cells. In order to analyze the role of the RGD sequence in FMDV infection of cells in more detail, 13 mutations within or near the RGD sequence of virus type O1Kaufbeuren were designed by using a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
