Article
Transgenic Mice Overexpressing the β1-Adrenergic Receptor in Adipose Tissue Are Resistant to Obesity
1 Jan 1997
Abstract excerpt
The ratio of alpha- to beta-receptors is thought to regulate the lipolytic index of adipose depots. To determine whether increasing the activity of the beta 1-adrenergic receptor (AR) in adipose tissue would affect the lipolytic rate or the development of this tissue, we used the enhancer-promoter region of the adipocyte lipid-binding protein (aP2) gene to direct expression of the human beta 1 AR cDNA to adipose...
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