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Article

Specific repression of the preproendothelin-1 gene in intracranial arteriovenous malformations.

Journal of neurosurgery - 1 Jan 1997

Rhoten R L, Comair Y G, Shedid D, Chyatte D, Simonson M S

Abstract excerpt

Cerebrovascular arteriovenous malformations (AVMs) display abnormal vascular development and dysautoregulation of blood flow. Genetic mechanisms that contribute to the pathogenesis and phenotype of cerebral AVMs are unknown. As a first step in understanding the pathophysiology of AVMs, the authors investigated the hypothesis that endothelial dysfunction-specifically, deregulation of endothelin-1 (ET-1)...

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Identifiers

PMID: 8988087
DOI: 10.3171/jns.1997.86.1.0101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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