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Article

Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: A quantitative approach

24 Dec 1996

Abstract excerpt

The epithelial amiloride-sensitive sodium channel (ENaC) controls transepithelial Na+ movement in Na(+)-transporting epithelia and is associated with Liddle syndrome, an autosomal dominant form of salt-sensitive hypertension. Detailed analysis of ENaC channel properties and the functional consequences of mutations causing Liddle syndrome has been, so far, limited by lack of a method allowing specific and...

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PMID: 8986818
DOI: 10.1073/pnas.93.26.15370

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Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: A quantitative approachPMID 8986818Read ↗

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