Type 2 diabetes mellitus: from genes to disease.

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Article

Type 2 diabetes mellitus: from genes to disease.

Pharmacological reports : PR - 1 Jan 2005

Malecki Maciej T, Klupa Tomasz

Abstract excerpt

The development of type 2 diabetes (T2DM) is determined by two factors: genetics and environment. The genetic background of T2DM is undoubtedly heterogeneous. Most patients with T2DM exhibit two different defects: the impairment of insulin secretion and decreased insulin sensitivity. This means that there are at least two pathophysiological pathways and at least two groups of genes that may be involved in the...

Topics

Deafness
Diabetes Mellitus, Type 2
Genetic Predisposition to Disease
Humans
Insulin
Insulin Resistance
Insulin Secretion
Severity of Illness Index

Source

Open in PubMed

Identifiers

PMID: 16415484

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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