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Article

Identification of residues in fission yeast and human p34cdc2 required for S-M checkpoint control.

Genetics - 1 Dec 1996

Basi G, Enoch T

Abstract excerpt

In fission yeast, regulation of p34cdc2 plays an important role in the checkpoint coupling mitosis to completion of DNA replication. The cdc2 mutations cdc2-3w (C67Y) and cdc2-4w (C67F) abolish checkpoint control without seriously affecting normal cell proliferation. However the molecular basis of this phenotype is not known. To better understand the role of p34cdc2 in checkpoint control, we have screened for...

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Identifiers

PMID: 8978030
DOI: 10.1093/genetics/144.4.1413
PMCID: PMC1207694

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