Article
Regulation of genomic instability in preneoplastic cells.
Cancer surveys - 1 Jan 1996
Tlsty T D
Abstract excerpt
Recent insights into the action of TP53 have uncovered signal transduction pathways that maintain genomic integrity. TP53 was the first gene demonstrated to be involved in these pathways, but mutation of several other genes can have a similar terminal effect. The characterization of these signal transduction pathways should provide further targets for the improvement of neoplastic diagnosis as well as therapeutic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
