[Progress of DNA based HLA typing methods].

Abstract excerpt

HLA genes exhibit high degrees of polymorphism, and a total of about 400 alleles have been identified at HLA-A, B, C and DR loci up to now. A number of DNA-based typing methods using specific primers, specific probes or restriction enzymes have been developed. In HLA class II allele typing, a few methods which are simple in handling and able to determine the alleles automatically, have been available. We have...

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