Article
An altered rpoS allele contributes to the avirulence of Salmonella typhimurium LT2.
Infection and immunity - 1 Jan 1997
Wilmes-Riesenberg M R, Foster J W, Curtiss R
Abstract excerpt
Virulent Salmonella typhimurium strains differ from the attenuated laboratory strain LT2 at the rpoS locus. It was previously shown that the rpoS gene in strain LT2 contains a rare UUG start codon (I. S. Lee, J. Lin, H. K. Hall, B. Bearson, and J. W. Foster, Mol. Microbiol. 17:155-167, 1995). This difference is responsible for the inability of LT2 to display a sustained log-phase acid tolerance response. We show...
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