Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Salmonella typhi rpoS mutant is less cytotoxic than the parent strain but survives inside resting THP-1 macrophages.

FEMS microbiology letters - 1 Apr 1998

Khan A Q, Zhao L, Hirose K, Miyake M, Li T, Hashimoto Y, Kawamura Y, Ezaki T

Abstract excerpt

Transcription of the stationary-phase sigma factor RpoS of Salmonella typhi increased in the macrophage. A single rpoS mutant of S. typhi was constructed to analyze the role of RpoS in intracellular multiplication of the bacterium and host cell killing. This mutant was sensitive to starvation, lo...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Macrophages
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Salmonella typhi

Share to Sigma Factor

Share to Transcription, Genetic

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 9561749
DOI: 10.1111/j.1574-6968.1998.tb12949.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9561749-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Salmonella typhi rpoS mutant is less cytotoxic than the parent strain but survives inside resting THP-1 macrophages.PMID 9561749Read ↗

Characterization of the RpoS status of clinical isolates of Salmonella enterica.Semantic proximity Read ↗

RpoS and RpoN are involved in the growth-dependent regulation of rfaH transcription and O antigen expression in Salmonella enterica serovar Typhi.Semantic proximity Read ↗

The live oral typhoid vaccine Ty21a is a rpoS mutant and is susceptible to various environmental stresses.Semantic proximity Read ↗

Role of RpoS in survival of Yersinia enterocolitica to a variety of environmental stresses.Semantic proximity Read ↗

The Legionella pneumophila rpoS gene is required for growth within Acanthamoeba castellanii.Semantic proximity Read ↗

RpoS co-operates with other factors to induce Legionella pneumophila virulence in the stationary phase.Semantic proximity Read ↗

RpoS is necessary for both the positive and negative regulation of starvation survival genes during phosphate, carbon, and nitrogen starvation in Salmonella typhimurium.Semantic proximity Read ↗

Fis regulates transcriptional induction of RpoS in Salmonella enterica.Semantic proximity Read ↗

Virulence and vaccine potential of Salmonella typhimurium mutants deficient in the expression of the RpoS (sigma S) regulon.Semantic proximity Read ↗

The periplasmic chaperone Skp is required for successful Salmonella Typhimurium infection in a murine typhoid model.Semantic proximity Read ↗

RpoS synthesis is growth rate regulated in Salmonella typhimurium, but its turnover is not dependent on acetyl phosphate synthesis or PTS function.Semantic proximity Read ↗

Functional heterogeneity of RpoS in stress tolerance of enterohemorrhagic Escherichia coli strains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.