Article
Functional interactions between the zinc fingers of Xenopus transcription factor IIIA during 5S rRNA binding.
RNA (New York, N.Y.) - 1 Dec 1996
Setzer D R, Menezes S R, Del Rio S, Hung V S, Subramanyan G
Abstract excerpt
We have used a collection of mutant forms of Xenopus transcription factor IIIA (TFIIIA) to study its interaction with 5S rRNA. This collection includes a set of nine mutant proteins, each of which contains a structural disruption in one of the nine zinc fingers of TFIIIA (broken-finger mutants), and a pair of complementary N- and C-terminal truncation mutants. Equilibrium and kinetic binding analyses in...
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