Article
Functional interactions between the zinc fingers of Xenopus transcription factor IIIA during 5S rRNA binding.
RNA (New York, N.Y.) - 1 Dec 1996
Setzer D R, Menezes S R, Del Rio S, Hung V S, Subramanyan G
Abstract excerpt
We have used a collection of mutant forms of Xenopus transcription factor IIIA (TFIIIA) to study its interaction with 5S rRNA. This collection includes a set of nine mutant proteins, each of which contains a structural disruption in one of the nine zinc fingers of TFIIIA (broken-finger mutants),...
Topics
- Animals
- Base Sequence
- Binding Sites
- DNA-Binding Proteins
- Half-Life
- Kinetics
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Protein Binding
- RNA, Ribosomal, 5S
- Ribonuclease, Pancreatic
- Transcription Factor TFIIIA
- Transcription Factors
- Xenopus
- Zinc Fingers