Article
Asparagine-344 is a key residue for ligand binding in keratinocyte growth factor receptor.
Biochemistry - 10 Dec 1996
Gray T E, Eisenstein M, Yayon A, Givol D
Abstract excerpt
The membrane proximal, immunoglobulin- (Ig-) like domain 3 of KGFR shows significant sequence similarity to the Ig light chain variable (V) domain. According to our model, based on this similarity, the F-G loop in KGFR corresponds to the complementarity determining region (CDR) 3 of the Ig V domain. The F-G loop in the membrane proximal domain of the keratinocyte growth factor receptor has previously been shown...
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