Article
Influence of angiotensin-converting enzyme and angiotensin II type 1 receptor gene polymorphisms on aortic stiffness in normotensive and hypertensive patients.
Circulation - 15 Aug 1996
Benetos A, Gautier S, Ricard S, Topouchian J, Asmar R, Poirier O, Larosa E, Guize L, Safar M, Soubrier F, Cambien F
Abstract excerpt
BACKGROUND: Clinical and experimental studies have demonstrated a major role of the renin-angiotensin system in the functional and structural changes of the large arteries in hypertension. Because genetic studies may help us to understand the mechanisms underlying the involvement of this system i...
Topics
- Adolescent
- Adult
- Aged
- Aorta
- Base Sequence
- Blood Pressure
- DNA Transposable Elements
- Diastole
- Female
- Genotype
- Humans
- Hypertension
- Male
- Middle Aged
- Molecular Sequence Data
- Muscle, Smooth, Vascular