Article
Autophosphorylation of Ser66 on Xenopus Myt1 is a prerequisite for meiotic inactivation of Myt1.
Cell cycle (Georgetown, Tex.) - 1 Feb 2006
Kristjánsdóttir Kolbrún, Safi Alexias, Shah Chirag, Rudolph Johannes
Abstract excerpt
Myt1 is a dual-specificity kinase that contributes to the regulation of the cell cycle by adding inhibitory phosphates to the cyclin-dependent kinases (Cdk/cyclins). Myt1 is found to be phosphorylated and less active in M-phase compared to interphase. Although Myt1 can be phosphorylated by several different kinases in vitro, it is not well understood how Myt1 is regulated in vivo. Additionally, the interplay...
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