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Article

Embryonic neuronal markers in tuberous sclerosis: single-cell molecular pathology.

Proceedings of the National Academy of Sciences of the United States of America - 26 Nov 1996

Crino P B, Trojanowski J Q, Dichter M A, Eberwine J

Abstract excerpt

One hallmark of tuberous sclerosis (TSC) is the presence of highly epileptogenic dysplastic cerebral cortex (tubers) composed of abnormally shaped neurons and giant cells. Mutation of the TSC gene (TSC2) may disrupt differentiation and maturation of neuronal precursors, since the TSC2 gene produc...

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Source

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Identifiers

PMID: 8943076
DOI: 10.1073/pnas.93.24.14152
PMCID: PMC19509

Genes

TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-8943076-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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