Phenotypic analysis of B-cells extracted from human periodontal disease tissue.

doi:10.1111/j.1399-302x.1991.tb00507.x

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Article

Phenotypic analysis of B-cells extracted from human periodontal disease tissue.

Oral microbiology and immunology - 1 Dec 1991

Gemmell E, Seymour G J

Abstract excerpt

B-cells extracted from periodontal disease tissue were analyzed for the presence of activation markers using a range of monoclonal antibodies. In adult periodontitis (AP), 6% of B-cells expressed the IL-2 receptor (CD25) compared with 1-2% in peripheral blood and healthy or marginal gingivitis (H/MG) gingival B-cells. There was also an increase in the mean percentage of IgD-positive B-cells and a decrease in CD21...

Topics

Adult
Antigens, CD
Antigens, Differentiation, B-Lymphocyte
B-Lymphocytes
Cell Adhesion Molecules
Fluorescent Antibody Technique
Fusobacterium nucleatum
Humans
Lectins
Lymphocyte Activation
Periodontitis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Porphyromonas gingivalis

Receptors, Complement

Receptors, Complement 3d

Receptors, Fc

Receptors, IgE

Receptors, Interleukin-2

Source

Open in PubMed

Identifiers

PMID: 1668249
DOI: 10.1111/j.1399-302x.1991.tb00507.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1668249-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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